Human Performance Alliance at Oregon Recruitment

The Wu Tsai Human Performance Alliance at the Knight Campus at the University of Oregon is currently offering the following employment opportunities:

In Vivo Models - Research Assistant/Associate
The Research Assistant or Associate will work closely with Associate Professor/Associate Director Nick Willett to manage and implement pre-clinical research and assessment across multiple research teams and projects. The position will help manage a regenerative rehabilitation facility within the Human Performance Initiative to include systems to implement pre-clinical rehabilitation regimens and evaluate functional and behavioral-related outcomes.

Performance Organoid - Research Associate
The Research Associate will work closely with Associate Professor/Associate Director Nick Willett on the Regenerative Rehabilitation Moonshot program of the Wu Tsai Human Performance Alliance. This position will manage and implement 3D culture systems for performance organoid research and assessment across multiple research teams and projects. 

Postdoctoral Scholar Open Pool - Regenerative Rehabilitation Moonshot
The Alliance at Oregon is recruiting three (3) postdoctoral fellows for several recently funded collaborative projects. Qualified candidates will have significant laboratory experience in regenerative medicine, biomechanics, biomarker assays, and/or preclinical models.   

  • Musculoskeletal Regenerative Rehabilitation – The objective of this program is to restore function to damaged musculoskeletal tissues through development of novel evidence-based treatments that combine regenerative therapies and physical rehabilitation protocols.  For each project, coordinated 3D bioprinted patient-specific in vitro models, novel sensor-enabled preclinical models, instrumented rehabilitation systems, and predictive multivariate modeling techniques will be used to optimize functional recovery from injuries to bone, muscle, tendon/ligament, and cartilage.  The Regenerative Rehabilitation program is part of the new $220 million Wu Tsai Human Performance Alliance.   
  • Immunoengineering Strategies for Musculoskeletal Trauma - The goals of this NIH-funded project are to investigate (i) how the development of systemic immune dysregulation and immunosuppression relates to functional bone regeneration and (ii) how systemic immunomodulation impacts the immune system and regenerative outcomes following severe musculoskeletal trauma.  This project combines established pre-clinical composite trauma models, systemic cellular and cytokine biomarkers of immune dysregulation, advanced machine learning algorithms, and nanoparticle-mediated immunomodulatory strategies to enhance functional regeneration following severe musculoskeletal injuries. 
  • Post-Traumatic Osteoarthritis - The goals of this research are to develop early interventions for joint trauma that accelerate healing and reduce or even prevent downstream post-traumatic osteoarthritis. We are developing joint-specific, patient-specific in vitro model systems as well as in vivo preclinical injury models and using these to perform high throughput therapeutic testing. Other work involves identifying early biomarkers and cell signaling pathways that predict osteoarthritis to formulate candidate therapies and delivery vehicles that specifically target affected joint tissues. We are also exploring combination treatments that would synergize exercise, intra-articular injectables, and modulated movement biomechanics to reduce pain, pathologic locomotion, and degenerative structural joint conditions.  This research is supported by the Wu Tsai Human Performance Alliance. 

Postdoctoral Scholar - Willett Lab
The Postdoctoral Scholar will be responsible for conducting research and technical activities related to sponsored projects in Dr. Willett’s lab and on a project under the Regenerative Rehabilitation Moonshot program of the Wu Tsai Human Performance Alliance. They will perform in vitro and in vivo research on regenerative engineering and rehabilitation technologies, conduct data analysis and collaborate on reporting findings and discoveries in written and verbal form; and will manage, maintain and provide technical expertise for Willett lab equipment, protocols, and programs.