Featured Speakers - Oregon Bioengineering Symposium

Oregon Health & Science University

 

laura heiser

Laura Heiser

Associate Professor of Biomedical Engineering, School of Medicine
Vice Chair, Biomedical Engineering, School of Medicine
OHSU Center for Spatial Systems Biomedicine
Program Co-Leader, Quantitative Oncology, OHSU Knight Cancer Institute, School of Medicine

Dr. Heiser's research focuses on genomic and epigenomic changes that cause breast cancer, with the goal of identifying pathways and aberrations associated with therapeutic response and resistance in cancer. In her studies, she uses an integrative systems biology approach to understand cancer as a complex system. Dr. Heiser is also an active member of the DREAM Consortium, which is a community-based effort to rigorously assess and advance algorithms in computational biology.

 

jeremy goecks

Jeremy Goecks

Associate Professor of Biomedical Engineering and Computational Biology Program, School of Medicine
Knight Cancer Institute, Oregon Health & Science University

Dr. Jeremy Goecks is an Associate Professor of Biomedical Engineering and Computational Biology at Oregon Health & Science University (OHSU). He directs informatics for OHSU’s precision oncology program and has leadership positions in several national/international computational biology and cancer projects funded by NIH and NSF. He is a lead investigator for the Galaxy Project (http://galaxyproject.org), a Web-based computational workbench used by thousands of scientists throughout the world.

 

carolyn

Carolyn Schutt Ibsen

Assistant Professor of Biomedical Engineering, Oregon Health and Science University
Cancer Early Detection Advanced Research Center (CEDAR), OHSU Knight Cancer Institute
Biomedical Engineering Graduate Program Faculty

Carolyn Schutt Ibsen joined OHSU in 2018 as an Assistant Professor in the Department of Biomedical Engineering. She holds a joint appointment with the Cancer Early Detection Advanced Research Center (CEDAR) in the Knight Cancer Institute. Her research group is focused on developing energy-responsive biomaterial platforms for tumor modeling and tissue engineering with particular focus on dynamic stimuli-responsive materials that can be controlled remotely and noninvasively. Her research interests include acoustically-active colloid systems, tissue-engineered models of cancer progression, stimuli-responsive materials to guide tissue regeneration, and 3-D bioprinting. Dr. Schutt Ibsen additionally serves on the International Alliance for Cancer Early Detection (ACED) Training and Education Working Group. Prior to OHSU, Dr. Schutt Ibsen completed a Whitaker International Postdoctoral Fellowship at Imperial College London, working with biomaterials for engineered tissue and regenerative medicine in the group of Prof. Molly M. Stevens. Dr. Schutt Ibsen holds a Ph.D. in Bioengineering from the University of California, San Diego where she was named a Siebel Scholar and NSF GRFP Fellow and received the Shunichi Usami Thesis Award. Her graduate work focused on the development of energy-responsive nanomaterials for cancer therapy and diagnostics using light, ultrasound, and their combination

 

kenton gregory

Kenton Gregory

Professor of Biomedical Engineering, School of Medicine
Director, RG.Regenerative Medicine

Kenton Gregory, Ph.D., is an internationally accomplished physician-bioengineer, whose landmark research breakthroughs include the development of life-saving medical products for troops in the battlefield. As director of the Center for Regenerative Medicine, Dr. Gregory directs efforts to advance autologous stem cell treatments to safely regenerate hearts damaged by heart attacks and cardiomyopathies that cause heart failure. He has advanced pioneering work to regenerate arms and legs severely damaged from battlefield blast injuries—work that could easily be translated to civilian extremity injuries to accelerate and improve healing. He is also directing efforts to regenerate skin after burn injuries, lung tissue after acute lung injury and prevent paralysis after nerve and spinal cord injuries.

Dr. Gregory received his undergraduate degree in engineering and doctorate in medicine from the University of Southern California. He completed his internship and residency in internal medicine and held a fellowship in cardiology at the Wadsworth Veterans Administration Hospital in Los Angeles. He completed an additional research fellowship in cardiology at the Irvine Medical Center in Orange, California. Dr. Gregory has held teaching positions at the University of California, Irvine Medical School, and Harvard University School of Medicine, and served as staff cardiologist at Massachusetts General Hospital. Dr. Gregory holds over 20 domestic and international patents, has served as principal investigator on five FDA-sponsored clinical trials, and has received more than $50 million in grants. Among his many accomplishments, Gregory has launched seven spin-off companies since 1991—three headquartered in Oregon.

Oregon State University

 

maude david

Maude David

Assistant Professor, Department of Microbiology

Maude David received her PhD in 2010 from the Ecole Centrale de Lyon, University of Lyon, France, with Prof. T.M. Vogel, on the origin of the dehalogenases and bioremediation of chlorinated solvent. Her grad-school work focused on the bacterial adaptation to chlorinated compounds at the genome (evolution mechanisms) and community (bioremediation) level. After graduation, she became a post-doctoral fellow at Lawrence Berkeley National Laboratory with Prof. Janet Jansson. Her work looked at the impact of climate change on soil microbial ecology and specifically at how altered precipitation affect carbon cycle using meta-“omics” analysis of microbial carbon cycling responses. In 2014, she started to work on the impact of the gut microbiome in autism in 2014 with Dennis Wall at Stanford School of Medicine, where she also worked on evolutionary constraints on human genome. She started as an assistant professor at Oregon State University in January 2018. Her expertise lays in microbiology, bioinformatics and genomics, using machine learning and multivariate analysis in order to integrate metagenomics, metatranscriptomics and metaproteomics and understand microbial community functions.

 

ben dalziel

Ben Dalziel

Assistant Professor, Department of Integrative Biology

Benjamin Dalziel has broad interests in ecological and evolutionary dynamics, particularly related to the health of human and animal populations, and to the maintenance of biodiversity. He is particularly interested in (i) the ecology and evolution of infectious diseases, especially the impact of host population structure on pathogen spread and diversification and (ii) how collective behavior affects trophic interactions and ecosystem stability.

 

stephen ramsey

Stephen Ramsey

Associate Professor, Computer Science and Biomedical Sciences

Stephen originally trained in physics and mathematics at Brown University and the University of Maryland followed by a postdoc in computational genomics at the University of Washington. As a scientist at the Institute for Systems Biology and the Center for Infectious Disease Research, Stephen worked on computational methods for mapping gene regulatory networks. At OSU, Stephen holds a dual appointment in the Department of Biomedical Sciences and in the School of Electrical Engineering and Computer Science. Stephen's work has been recognized by multiple awards including an NIH Career Development Award, a PhRMA New Investigator Award, and an NSF CAREER award.

 

david hendrix

David Hendrix

Associate Professor, Biochemistry and Biophysics

David Hendrix employs a broad range of computational approaches, from machine learning to data mining, to investigate questions concerning genomics and gene regulatory systems. His lab seeks to use computational biology and bioinformatics to uncover new mechanisms of gene regulation, as well as validate known biology. They develop motif-finding algorithms and pipelines to understand how promoters and regulatory elements operate, as well as creating new approaches for the analysis of deep-sequencing data to increase knowledge of the principles underlying transcription initiation, transcriptional gene silencing, post-transcriptional gene silencing and Polymerase stalling/pausing. One major objective of our lab includes furthering the understanding of the structure, function and mechanisms of action of non-coding RNAs, both large and small. The past decade has seen the discovery of numerous non-coding RNAs whose functions are largely unknown. We aim to discover new non-coding RNAs and gain insight into the roles of these molecules in gene regulation by developing novel computational approaches for the integration of structural predictions, genome-wide sequence analysis, and deep sequencing data.

University of Oregon

 

karen guillemin

Karen Guillemin

Professor, Department of Biology
Member, IMB

Karen Guillemin is a professor in the Department of Biology, member of the UO Institute of Molecular Biology and founding director of the Microbial Ecology and Theory of Animals Center for Systems Biology, which is funded by the National Institutes of Health. Guillemin pioneered the use of zebrafish as a model organism for studying the interactions of animals with their resident microbes or “microbiomes.” In particular, Guillemin’s research group investigates how resident bacteria influence development, metabolism, and immunity. Working with her UO colleagues across campus, Guillemin has helped in developing new microscopic technologies that have allowed for live imaging of the bacteria in the zebrafish gut. Efforts to understand these interactions in normally developing hosts such as zebrafish can provide insights into what goes wrong in many human disease states, particularly in chronic inflammatory conditions, diabetes, and cancer. Information gained through studies done in Guillemin’s lab eventually may guide efforts of researchers in the Knight Campus to develop new approaches, informed by microbiome science, for treating and curing a variety of human diseases.

 

mike hahn

Mike Hahn

Associate Professor, Department of Human Physiology Bowerman Sports Science Clinic Director

Mike Hahn is an academic expert in sports science and biomechanics. He is an associate professor of human physiology and the director of the Bowerman Sports Science Clinic. Hahn’s research expertise is broadly defined by the mechanics and neuromuscular control of human locomotion. Current research projects are focused on the areas of prosthetic engineering, treatment outcomes in ankle osteoarthritis, neural control of powered prosthetic/orthotic devices, and mechanisms of locomotor adaptation after lower limb injury. He is currently leading a study seeking to identify athletes with the highest risk of developing stress fractures, which can keep athletes out of competition for multiple seasons.

 

nick allen

Nick Allen

Professor, Department of Psychology
Ann Swindells Professor; Director, Center for Digital Mental Health; Director of Clinical Training

Nick Allen is a leading researcher in the area of adolescent mental health, known especially for his work on adolescent-onset depression. His work aims to understand the interactions between multiple risk factors for adolescent mental health disorders, including stress, family processes, brain development, autonomic physiology, genetic risk, immunology, and sleep. He has also translated this research on risk factors into innovative preventative approaches to adolescent mental health. He is the Director of the Center for Digital Mental Health, where his work focuses on the use of mobile and wearable technology, and his group has developed software tools that combine active and passive mobile sensing methods to provide intensive longitudinal assessment of behavior with minimal participant burden. He is the Co-Founder and CEO of Ksana Health, a UO linked startup company that develops software to support innovative research and intervention in mental health. The ultimate aim of developing these technologies is to facilitate the development of a new generation of “just-in-time” behavioral interventions for early intervention and prevention of mental health problems.

 

parisa h

Parisa Hosseinzadeh

Assistant Professor, Phil & Penny Knight Campus for Accelerating Scientific Impact

Parisa Hosseinzadeh is a computational biochemist invested in developing new tools to enhance human life, especially through structure-guided rational protein/peptide design and the use of large data. As an undergraduate student, Parisa was trained as a molecular biologist. Her interest in proteins led to her graduate research on the rational design of metalloproteins in the lab of Dr. Yi Lu at the University of Illinois at Urbana-Champaign. Parisa’s research on altering second shell interactions to tune the activity of proteins provides a general guideline for tuning the redox potential of metal centers. As a postdoctoral fellow in the lab of Dr. David Baker at the Institute for Protein Design, she developed new computational tools to design structured cyclic peptides and used these peptides as specific inhibitors to target enzymes/proteins.